There is no real way to determine if someone will have an adverse reaction or side effect from taking a given med until they test it. It's our responsibility as patients to read and understand what those side effects and risks are and inform the doctor when they occur. Your doctor prescribes those medications based on your specific condition and what medications or combinations there of are proven to have the highest chance of success in treating your condition while weighing the associated risks. Virtually all heart medications have potential side effects that can be mild to serious.